[18F]SDM-8 / [18F]MNI-1126 / [18F]SynVesT-1

The GMP certified precursor for [18F]SDM-8 / [18F]MNI-1126 / [18F]SynVesT-1 (an [18F]-analog of UCB-J) and the reference standard for SDM-8 / MNI-1126 are available.
















[18F]SynVesT-1

Cai Z.; Li S. et al.
Synthesis and Preclinical Evaluation of an 18F-Labeled Synaptic Vesicle Glycoprotein 2A PET Imaging Probe: [18F]SynVesT-2
ACS Chem. Neurosci. 2020, 11, 4, 592-603
Publication Date:January 21, 2020
https://doi.org/10.1021/acschemneuro.9b00618


[18F]MNI-1126
Constantinescu, C.C.; Tresse, C.; Zheng, M. et al.

Development and In Vivo Preclinical Imaging of Fluorine-18-Labeled Synaptic Vesicle Protein 2A (SV2A) PET Tracers

Mol Imaging Biol (2019) 21: 509.

https://doi.org/10.1007/s11307-018-1260-5


[18F]SDM-8

Li, S.; Cai, Z.; Wu X.; Holden, H.; Pracitto, R.; Kapinos, M.; Gao, H.; Labaree, D.; Nabulsi, N.; Carson, R.E.; Huang, Y.

Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates

ACS Chem. Neurosci. 2019, 10, 3, 1544-1554

https://doi.org/10.1021/acschemneuro.8b00526

Citation: "Radiolabeling of the trimethyltin precursor was more successful compared to several other precursors."